New research suggests that certain antidepressants can accelerate cognitive decline in people with dementia. At the same time, some drugs appear to be less harmful than others, which can help doctors make better treatment decisions, according to the study.

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[–] orbituary@lemmy.dbzer0.com 18 points 1 day ago (6 children)

We have a raging family debate about this going on right now. My brother is an expert in this field. My mom is on escitalopram.

The SSRI escitalopram was associated with the fastest cognitive decline, followed by the SSRIs citalopram and sertraline.

[–] Redditsux@lemmy.world 6 points 1 day ago (5 children)

Boy that would some family debate. What's holding her back from switching to others suggested here?

[–] orbituary@lemmy.dbzer0.com 8 points 1 day ago (4 children)

Well, the fact that its a relatively new debate. Also, this is a new article to me. My brother works in the pharmaceutical field as a scientist and medical liaison. He says Trintellex is what she probably needs, seeing as cita/escita are a bad mix with alcohol.

[–] Limerance@piefed.social 2 points 1 day ago (1 children)

cita/escita are a bad mix with alcohol

How bad though?

[–] orbituary@lemmy.dbzer0.com 5 points 1 day ago (1 children)

How long is a string? Mileage varies by person.

[–] Limerance@piefed.social 1 points 1 day ago (1 children)

Sure. What's the mechanism of the adverse effects? Alcohol is always bad. Is it just extra taxing on the liver? Or is something specific going on?

[–] Redditsux@lemmy.world 1 points 23 hours ago

Neuro scientists say any amount of alcohol is bad for the brain. My understanding is that alcohol damages dendrites and synapses in the brain.

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