The instance seems to be mostly right wing trolls. I know defederating is unpopular but I don't think much is to be lost in this case and it can save the mods some headaches.
Edit: the response on exploding-heads.com to my reporting of transphobia. Courtesy of the "second in command"
I’m as leftist as they come and I do not support this action. If you don’t want to see it, mute the instance rather than creating an echo chamber.
How does one mute an entire instance?
I’m not actually sure, honestly. Maybe mute the users instead if the instance isn’t possible to mute.