this post was submitted on 07 Jun 2025
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[–] RBWells@lemmy.world 48 points 6 days ago (5 children)

Not "even paracetamol". ESPECIALLY paracetamol.

Tylenol/acetaminophen/paracetamol is both weak ass painkiller and really dangerous because the overdose line is low. Here they put it in synthetic opioid drugs, it doesn't help with pain but does make them more dangerous.

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[–] BoxOfFeet@lemmy.world 20 points 6 days ago (5 children)

I think what's extra dangerous about Tylenol is that it doesnt feel like it's doing anything. When it works, some minor pain goes away, or maybe your fever goes down. But there's no side effects that you really feel, so I bet people get a false sense of security with it. Like, oh it isn't giving me opioid euphoria, or knocking me out. And you can just buy as much as you want, no restrictions. It must be perfectly safe.

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[–] MangioneDontMiss@lemmy.ca 20 points 6 days ago (3 children)

how the fuck did they find a donor so fast???

[–] Default_Defect@midwest.social 5 points 5 days ago (5 children)

I got a heart transplant about 18 hours after being added to the list.

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[–] steeznson@lemmy.world 8 points 5 days ago (2 children)

Couldn't they have given the liver to someone who was less of an idiot?

[–] RealSpiderLane@lemmy.zip 7 points 5 days ago

Ex alcoholic and “cirrhosis survivor” here. (I hate that latter term.)

I’m stunned that this situation went down how it did.

I had the full jaundice package when I finally went into the hospital and agreed to detox. I was told I would have to be booze-free for a minimum of six months to be considered for a transplant of any kind; both my liver and kidneys were in concerning shape.

They told me the timeframe for actually being considered was more like two years; there’s basically a board of trustees for each state, they review every case requesting an organ transplant and decide who gets what. (It’s literally a death panel, haha.)

No matter how good I was/am, I would still be at the very lowest priority. They’d have to have available livers as far as the eye can see for me to have a realistic chance. There is no actual chance I would ever get a donor liver, and I don’t want one.

I was dumb. I did it completely to myself. It’s not as simple as “you could’ve quit anytime you wanted,” trying to do that with alcohol is extraordinarily dangerous, BUT I did indeed do this to myself. It would be galactic levels of unethical and immoral for me to be trying to take a donor liver away from ANYONE.

I have since recovered way past the expectations of any medical personnel who worked on me during that time. July 1 will be two years alcohol-free for me.

My point in all of this is that I’m honestly having trouble believing this guy got this transplant at all, let alone so fast.

[–] Bgugi@lemmy.world 4 points 5 days ago

Organs don't keep... If they got the donor it probably meant there wasn't anybody else queued up.

[–] Flamekebab@piefed.social 36 points 6 days ago (9 children)

It's bizarre to me that someone can make it to adulthood without knowing that paracetamol specifically is no fucking joke.

[–] raltoid@lemmy.world 25 points 6 days ago* (last edited 6 days ago) (1 children)

People look up resources on them and see that the recommended max dose of ibuprofen is lower than paracetamol per day in weight of the active ingredient and stop reading.

They don't get to the part about how the effect per weight isn't the same. Or how damaging paracetamol can be for the liver if you take it regularly or go over the recommend limit. Heavy drinkers especially don't take into account the extra stress on their liver, which is a contributor to the 400-500 deaths it causes every year in the US alone.

Meanwhile ibuprofen makes you feel sick and want to vomit once you start to go over the recommended limit. And if you reach that stage, you basically just stay hydrated to keep your kidneys going and wait for it to pass. Since it usually takes another 2-3 times as much to for the severe effects to occur.


To quote Scrubs:

Dr. Cox: Did you just page me to ask me how much ibuprofen to give Mrs. Lenzner here?

Sunny: Well, I was worried it would exacerbate the patient's

Dr. Cox: It's ibuprofen! Here's what you do. When she wakes up, get her to open her mouth nice and wide, then get some of those ibuprofen pills in your hands and throw them at her. Whatever sticks in there, that's the correct dosage.

And in the pilot episode, it was J.D. and regular strength Tylenol.

[–] Dozzi92@lemmy.world 8 points 6 days ago (3 children)

Acetaminophen (paracetamol) is definitely tough on the liver. I remember during EMT classes (well, I kinda remember, was 20 years ago) having one of the paramedics in the class talking about how it was worse on the liver than heroin. Now yes, heroin obviously has other downsides, but it's just crazy to think about. I have always limited my intake of it, never take it if I've been drinking, that sort of thing. The issue is that it's not exactly common knowledge. I know plenty of people who would drink and take some Tylenol at bedtime to kill the hangover. Not a good habit.

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[–] dutchkimble@lemy.lol 21 points 6 days ago (8 children)

Is this real? Who gets a liver donor in 4 days?

[–] Rainbowblite@lemmy.ca 12 points 6 days ago (1 children)

The liver damage is very believable but a liver transplant after 4 days is absurd.

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[–] sxan@midwest.social 28 points 6 days ago (7 children)

You know what else is stupid? Pain management in the US. I get that you need to be careful about addiction, but the idea that people should have to suffer pain because we're having a pain medication "reefer madness" spasm is idiocy.

The guy just kept taking them until his teeth stopped hurting. Why is the alternative that he just has to put up with being in pain?

[–] sulgoth@lemmy.world 27 points 6 days ago (1 children)

The fact that the drug companies lied about the addictiveness of their product so doctors were handing them out like candy didn't help.

[–] Dozzi92@lemmy.world 11 points 6 days ago

Yeah, it was rampant here in Jersey, and we're definitely still feeling the effects. Things that didn't need opiates got opiates. And guess what? Lotta people all of a sudden need them for life. And it wasn't just Oh, here's your script. Doctors were knowingly abusing it for profit. So like with most things in life, some people ruin it for everyone else.

[–] RBWells@lemmy.world 10 points 6 days ago (4 children)

Yes it is. I have had, over my 40 years as migraineuse (they started in my teens) 5 intractable migraines. Meaning less than once every 5 years I get one that lasts days, I cannot eat or drink, just puke. I used to be able to go to my doctor and get shot up with opiates and Phenergan, so much of it, they would do one dose, come back later, another, another, another, until finally I would say "it still hurts but I don't care" and go home nodding like a junkie, sleep and wake up with no headache, and, importantly, NO desire for more drugs.

Now the opiates are not allowed because they didn't work. But nothing works on the status migraine. Now they give you a cold cocktail IV of some sort of Advil and nausea medicine and it doesn't work either, and costs $2,000 because it can only be done in the emergency room not the doctor office.

It's adding insult to injury. There has to be some way to make these available for acute situations at least.

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[–] joel_feila@lemmy.world 9 points 6 days ago

We have never had good pain management here. Claiming babies can't feel pain, black people hace higher pain tolerance, etc etc. then we swung into really permissive use with oxycodone for a while.

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[–] ColeSloth@discuss.tchncs.de 20 points 6 days ago (11 children)

He's lucky it was just his liver. People who overdose or try to commit suicide with it are not in for a good time or quick death and after it's absorbed into your body it will cause a systemic shutdown of several organs like the kidneys and pancreas. Not just the liver, and there's absolutely no way to counteract this after that first 36 hours. You will die (you aren't getting all of the organs replaced) and it will take days before you succumb. No antidote or life support or anything can be done for you.

You'll feel fine the first day but may have some vomiting. By day 3 the jaundice and stomach pain sets in as the liver is first to show signs of the organs failure and it's no longer possible to counteract the drug. By the fourth day your organs start shutting down and you'll have much more pain and vomiting. All that can be done is get your affairs in order because you'll be dead and in pain while you wait around to die and regret your suicide.

I say suicide because it's almost always intentional. It usually takes 40 325mg pills to cause this, although the liver damage can be caused with 20+ pills in an adult, generally. If you think you've possibly overdosed get to the hospital quick and tell them what you've taken so they can start you on Acytylcystine. If you "feel fine" after the first day or so and think you're all good you may be wrong and when day Tyree rolls around and your feeling bad or jaundiced your liver is already wrecked and can't be fixed.

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[–] douglasg14b@lemmy.world 16 points 6 days ago (3 children)

Sounds like American healthcare to me.

You either cope, and probably cause irreparable hard to yourself, or you go to the clinic or ER and get labeled a drug seeker.

[–] the_crotch@sh.itjust.works 17 points 6 days ago (2 children)

Americans don't call it paracematol, they call it acetaminophen or just tylenol. This is from the UK.

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[–] Shardikprime@lemmy.world 12 points 6 days ago* (last edited 6 days ago) (1 children)

My brother in Christ, the paracetamol box LITERALLY says to never go more than 4 grams (4000 mg) in a 24hs period on any mg pills presentation

And as far as I see, that's a general rule with everything. Even those caramels for sore throat or reflux pills, where you'd need to eat thousands in a day to overdose, say the same

Don't fuck with medicine dudes

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[–] shadowedcross@sh.itjust.works 18 points 6 days ago (2 children)

It's people like this who make other people think any amount of painkillers is bad, and seem to get a sense of superiority about them for never taking any.

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[–] joel_feila@lemmy.world 11 points 6 days ago (8 children)
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[–] leadore@lemmy.world 10 points 6 days ago* (last edited 6 days ago) (1 children)

How much is a "packet"? edit: never mind, I found several conflicting answers in the other comments, no need to add even more and add to the confusion.

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[–] Alaik@lemmy.zip 8 points 6 days ago (4 children)

ITT: People who don't know the difference between acute and chronic ODs and how a smaller amount over a long period can hurt you. 325mg APAP x4 will not kill you short term.

The problem was taking it every day over a long period.

Its still fucking stupid though.

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[–] ShankShill@sh.itjust.works 6 points 6 days ago (8 children)

My daughter's dog that is a climber got on a shelf and knocked a basket off that had a large bottle of Tylenol in it. She chewed the bottle up.

I got home and saw some pills and a demolished bottle on the ground. Vet tech friend said to induce vomiting with hydrogen peroxide.

Didn't have any of that, but I did have some minty mouthwash with peroxide and no xylitol in it. Dog willingly drank it, puked with foam, drank a bit more, puked more foam, then I dug through the mess.

No pills or any sign of the color on the pills. She's still kicking.

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