Well, I cannot comment about PopOS because I simply don't know how it is, but Bazzite on desktop has been great. I didn't need to install anything related to gaming because it already comes with everything on it.

Pretty much anything I needed is on the discovery store and it's handled like the app store on Android, so no headache of messing it up with installations or worrying about updates. Although, Bazzite is an immutable OS so anything that you need to install that's not on the store can be a headache.

Also, my computer is an old laptop, so I got a performance boost as the system feels way smoother now than with Windows.

About games, I played some indie games on Steam and Lutris and it worked flawlessly. But do note that for more recent systems, it appears to be some headaches, especially with NVIDIA graphics cards. I only play new games on streaming services, so I don't have those problems. But I do have some problems with the streaming service using my 8BitDo controller, but it's not related to the system, it's related to the service's bad drivers. When I stream the game using Steam, it's smooth sailing.