I've had decent results using the printer and filament-manufacturer specific settings from orca slicer OOTB with no tuning on my anycubic kobra 2
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Il not even sure it's possible. It might work for ballpark, "decent enough" settings but would that even be better than factory settings?
I have 2 PETG colors from the same brand that behave widely differently. I've seen batches of the exact same brand, material and color needing different temperature and retraction settings.
Each printer seems unique and seems to need slightly different settings than the next. Mechanical components wear out and drift out of tune. Thermocouples and hall sensors can drift. When rebuilding or upgrading your hotend, chances are you'll need to recalibrate everything. Belts need regular retensioning and that might affect motion settings.