alberttcone

joined 11 months ago
[–] alberttcone@sh.itjust.works 4 points 1 month ago

It’s a bit complicated, both because some studies just asked people if they are ‘natural redheads’ and didn’t actually test whether they have the MCR1 mutation and because it depends on the mechanism of action of the drug. Some sedatives are less effective, so need higher doses, but the majority of opioid based pain control drugs require lower doses in redheads.

https://www.nih.gov/news-events/nih-research-matters/study-finds-link-between-red-hair-pain-threshold

[–] alberttcone@sh.itjust.works 7 points 1 month ago (2 children)

Redheads need a lower opioid dose than the general population to achieve the same effect. At least those who are redheads because of a mutation in their MCR1 gene, which is about 75%, IIRC. Interestingly, the same mutation group also have worse tolerance of cold, which seems odd given that scotland is the global redhead centre!

[–] alberttcone@sh.itjust.works 1 points 3 months ago (1 children)

It was the Honda FRV and I still have one. I also had a Multipla. Both are good, in their own quirky ways. Both have slightly narrower seats than a normal car; the honda slightly narrower, but more supportive, have heating and are leather. Both are very car-like to drive, but the Honda has way better engines and better reliability. That said, getting parts for the FRV is a pain, because there weren’t many made and the wider body means that a surprising number aren’t shared with other Honda models if the same era.

Given a choice, as a practical family car, I’d take the FRV over the multipla. I do have a soft spot for the multiplugly though.

[–] alberttcone@sh.itjust.works 12 points 4 months ago (1 children)

I can’t offer any comparison between the Us and the UK, but I have some experience of having a neurodivergent child in the UK. We live in the NE of England, an area which is on average pretty deprived by UK standards*, however the support from the primary and secondary state schools we have used has been exceptional, with additional staffing as required and sensitive adaptions to needs throughout. There was some bullying at one point in primary school, but that was dealt with promptly and effectively and strategies were put in place to avoid social isolation - things it would never have occurred to me to do. The support for LGBTQ kids in secondary has also been pleasantly surprising - to the point that those who try to pick on trans kids find themselves becoming persona non grata pretty quickly.

There are some pretty huge cultural differences between the UK and the US, as you will know, and I suspect adjusting to those are going to be the primary problem in the move, rather than the support for a neurodivergent or SEN child.

*I feel like I should stand up for my adopted North-East; whilst it’s true that there are deprived areas, the NE is a beautiful place, the people are friendly and welcoming and the cost of living is low compared to many areas. The accents are proper canny too!

[–] alberttcone@sh.itjust.works 7 points 8 months ago* (last edited 8 months ago) (3 children)

I think that it’s implicit that the volume of Godzilla would increase; we need to assume that the bounding layer has a degree of elasticity and that that the matter displaced by the flotation cavity will expand into that, reducing the net density.

Mighty Godzilla, with power untold

Rises through the waves; his powers unfold

Hidden muscles in clever design

Create a new chamber as they realign

Inflating his body, a titanic display

Defying the depths, he floats up and away

No long bound by the oceans’s might

Godzilla soars, a triumphant sight!

[–] alberttcone@sh.itjust.works 2 points 9 months ago

Yeah, it’s been pretty universal in the UK for at least the last couple of years. Not sure where this idea came from.