Do you have plum blight in your area? Something to be aware of if planting native Prunus species. If you don't have problems with fungus there, then I definitely recommend Prunus americana.
I also second the suggestion of Diospyros virginiana. I've heard praise of the 'Meader' cultivar in particular.
Are you familiar with Amelanchier laevis? It should be native to Ohio.
Is "spikes" a euphemism for durian?